CMBL (NM_138809) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201711L3V

Lenti ORF particles, CMBL (Myc-DDK tagged) - Human carboxymethylenebutenolidase homolog (Pseudomonas) (CMBL), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CMBL
• Synonyms: JS-1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_138809
• ORF Size: 735 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201711).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_138809.3, NP_620164.1
• RefSeq Size: 4047
• RefSeq ORF: 738
• Locus ID: 134147
• Domains: DLH
• Protein Pathways: Metabolic pathways
• MW: 28 kDa
• Gene Summary: CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]). [supplied by OMIM, Apr 2010]