RAB23 (NM_016277) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC201922L1V
- LentiORF®
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Lenti ORF particles, RAB23 (Myc-DDK tagged) - Human RAB23, member RAS oncogene family (RAB23), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | RAB23 |
Synonyms | HSPC137 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_016277 |
ORF Size | 711 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC201922).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_016277.3, NP_057361.3 |
RefSeq Size | 4837 |
RefSeq ORF | 714 |
Locus ID | 51715 |
Domains | ras, RAN, RAS, RHO, RAB |
Protein Families | Druggable Genome |
Protein Pathways | Hedgehog signaling pathway |
MW | 26.7 kDa |
Gene Summary | This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
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