DYRK3 (NM_001004023) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC201997L1V

Lenti ORF particles, DYRK3 (Myc-DDK tagged) - Human dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (DYRK3), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: DYRK3
• Synonyms: DYRK5; hYAK3-2; RED; REDK
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001004023
• ORF Size: 1704 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201997).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001004023.1, NP_001004023.1
• RefSeq Size: 2301 bp
• RefSeq ORF: 1707 bp
• Locus ID: 8444
• Cytogenetics: 1q32.1
• Protein Families: Druggable Genome, Protein Kinase
• MW: 64 kDa
• Gene Summary: This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]