Betacellulin (BTC) (NM_001729) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202483L1V

Lenti ORF particles, BTC (Myc-DDK tagged) - Human betacellulin (BTC), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: BTC
• Synonyms: betacellulin; OTTHUMP00000160600
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001729
• ORF Size: 534 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202483).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001729.1, NP_001720.1
• RefSeq Size: 1323 bp
• RefSeq ORF: 537 bp
• Locus ID: 685
• Cytogenetics: 4q13.3
• Domains: EGF
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
• Protein Pathways: ErbB signaling pathway
• MW: 19.8 kDa
• Gene Summary: 'This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients. [provided by RefSeq, Nov 2015]'