CHRNB1 (NM_000747) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204040L1V

Lenti ORF particles, CHRNB1 (Myc-DDK tagged) - Human cholinergic receptor, nicotinic, beta 1 (muscle) (CHRNB1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CHRNB1
• Synonyms: ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000747
• ORF Size: 1503 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204040).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000747.2, NP_000738.2
• RefSeq Size: 2437 bp
• RefSeq ORF: 1506 bp
• Locus ID: 1140
• Cytogenetics: 17p13.1
• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• MW: 56.7 kDa
• Gene Summary: 'The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]'