Cathepsin G (CTSG) (NM_001911) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204881L2V

Lenti ORF particles, CTSG (mGFP-tagged) - Human cathepsin G (CTSG), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CTSG
• Synonyms: CATG; CG
• Vector: pLenti-C-mGFP
• ACCN: NM_001911
• ORF Size: 765 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204881).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001911.2, NP_001902.1
• RefSeq Size: 924 bp
• RefSeq ORF: 768 bp
• Locus ID: 1511
• Cytogenetics: 14q12
• Domains: Tryp_SPc
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome, Neuroactive ligand-receptor interaction, Renin-angiotensin system, Systemic lupus erythematosus
• MW: 28.8 kDa
• Gene Summary: 'The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014]'