HMG1 (HMGB1) (NM_002128) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC205918L4V
- LentiORF®
Lenti ORF particles, HMGB1 (mGFP-tagged) - Human high mobility group box 1 (HMGB1), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | HMGB1 |
Synonyms | HMG-1; HMG1; HMG3; SBP-1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_002128 |
ORF Size | 645 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC205918).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002128.4, NP_002119.1 |
RefSeq Size | 3428 bp |
RefSeq ORF | 648 bp |
Locus ID | 3146 |
Cytogenetics | 13q12.3 |
Domains | HMG |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Protein Pathways | Base excision repair |
MW | 24.9 kDa |
Gene Summary | 'This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]' |
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