CDHH (CDH13) (NM_001257) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206068L1V

Lenti ORF particles, CDH13 (Myc-DDK tagged) - Human cadherin 13, H-cadherin (heart) (CDH13), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: CDH13
• Synonyms: CDHH; P105
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001257
• ORF Size: 2139 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206068).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001257.3, NP_001248.1
• RefSeq Size: 4028 bp
• RefSeq ORF: 2142 bp
• Locus ID: 1012
• Cytogenetics: 16q23.3
• Domains: CA
• MW: 78.3 kDa
• Gene Summary: 'This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]'