Stanniocalcin 1 (STC1) (NM_003155) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206573L2V

Lenti ORF particles, STC1 (mGFP-tagged) - Human stanniocalcin 1 (STC1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: STC1
• Synonyms: STC
• Vector: pLenti-C-mGFP
• ACCN: NM_003155
• ORF Size: 741 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206573).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003155.2, NP_003146.1
• RefSeq Size: 3897 bp
• RefSeq ORF: 744 bp
• Locus ID: 6781
• Cytogenetics: 8p21.2
• Domains: Stanniocalcin
• Protein Families: Druggable Genome, Secreted Protein
• MW: 27.6 kDa
• Gene Summary: 'This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]'