BDNF (NM_170732) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206618L2V
- LentiORF®
-
Lenti ORF particles, BDNF (mGFP-tagged)-Human brain-derived neurotrophic factor (BDNF), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | BDNF |
Synonyms | ANON2; BULN2 |
Vector | pLenti-C-mGFP |
ACCN | NM_170732 |
ORF Size | 741 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206618).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_170732.3, NP_733928.1 |
RefSeq Size | 4125 bp |
RefSeq ORF | 744 bp |
Locus ID | 627 |
Cytogenetics | 11p14.1 |
Protein Families | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Transmembrane |
Protein Pathways | Huntington's disease, MAPK signaling pathway, Neurotrophin signaling pathway |
MW | 27.9 kDa |
Gene Summary | 'This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]' |
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