TFE3 (NM_006521) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206840L2V

Lenti ORF particles, TFE3 (mGFP-tagged) - Human transcription factor binding to IGHM enhancer 3 (TFE3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TFE3
• Synonyms: bHLHe33; RCCP2; RCCX1; TFEA
• Vector: pLenti-C-mGFP
• ACCN: NM_006521
• ORF Size: 1725 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206840).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006521.3, NP_006512.2
• RefSeq Size: 3467 bp
• RefSeq ORF: 1728 bp
• Locus ID: 7030
• Cytogenetics: Xp11.23
• Domains: HLH
• Protein Families: Druggable Genome, Transcription Factors
• MW: 61.5 kDa
• Gene Summary: 'This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]'