POLDIP1 (KCTD13) (NM_178863) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC206944L1V

Lenti ORF particles, KCTD13 (Myc-DDK tagged) - Human potassium channel tetramerisation domain containing 13 (KCTD13), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: KCTD13
• Synonyms: BACURD1; FKSG86; hBACURD1; PDIP1; POLDIP1
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_178863
• ORF Size: 987 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206944).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_178863.2, NP_849194.1
• RefSeq Size: 1745
• RefSeq ORF: 990
• Locus ID: 253980
• Protein Families: Ion Channels: Other, Transcription Factors
• MW: 36.4 kDa
• Gene Summary: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:19782033). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome (PubMed:19782033) Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission. [UniProtKB/Swiss-Prot Function]