MRCL3 (MYL12A) (NM_006471) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC207294L2V
- LentiORF®
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Lenti ORF particles, MYL12A (mGFP-tagged) - Human myosin, light chain 12A, regulatory, non-sarcomeric (MYL12A), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | MYL12A |
Synonyms | HEL-S-24; MLC-2B; MLCB; MRCL3; MRLC3; MYL2B |
Vector | pLenti-C-mGFP |
ACCN | NM_006471 |
ORF Size | 513 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207294).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006471.2, NP_006462.1 |
RefSeq Size | 1243 |
RefSeq ORF | 516 |
Locus ID | 10627 |
Domains | EFh |
Protein Pathways | Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton, Tight junction |
MW | 19.8 kDa |
Gene Summary | This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Dec 2014] |
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