SEC63 (NM_007214) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC208436L2V

Lenti ORF particles, SEC63 (mGFP-tagged) - Human SEC63 homolog (S. cerevisiae) (SEC63), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SEC63
• Synonyms: DNAJC23; ERdj2; PCLD2; PRO2507; SEC63L
• Vector: pLenti-C-mGFP
• ACCN: NM_007214
• ORF Size: 2280 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208436).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007214.3, NP_009145.1
• RefSeq Size: 6500
• RefSeq ORF: 2283
• Locus ID: 11231
• Domains: DnaJ, Sec63
• Protein Families: Transmembrane
• MW: 88 kDa
• Gene Summary: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]