Dystrophia myotonica protein kinase (DMPK) (NM_004409) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC209151L1V
- LentiORF®
-
Lenti ORF particles, DMPK (Myc-DDK tagged) - Human dystrophia myotonica-protein kinase (DMPK), transcript variant 2, 200ul, >10^7 TU/mL
Product Images
![](https://cdn.origene.com/img/defaults-img.jpg)
Other products for "DMPK"
Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | DMPK |
Synonyms | DM; DM1; DM1PK; DMK; MDPK; MT-PK |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_004409 |
ORF Size | 1887 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC209151).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_004409.2, NP_004400.4 |
RefSeq Size | 2874 bp |
RefSeq ORF | 1890 bp |
Locus ID | 1760 |
Cytogenetics | 19q13.32 |
Domains | pkinase, S_TK_X, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase |
MW | 69.4 kDa |
Gene Summary | 'The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2016]' |
Documents
Product Manuals |
FAQs |
Resources
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.