HRG (NM_000412) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210166L1V

Lenti ORF particles, HRG (Myc-DDK tagged) - Human histidine-rich glycoprotein (HRG), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: HRG
• Synonyms: HPRG; HRGP; THPH11
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000412
• ORF Size: 1575 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210166).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000412.2, NP_000403.1
• RefSeq Size: 2015 bp
• RefSeq ORF: 1578 bp
• Locus ID: 3273
• Cytogenetics: 3q27.3
• Domains: CY
• Protein Families: Secreted Protein
• MW: 59.6 kDa
• Gene Summary: 'This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. [provided by RefSeq, Nov 2014]'