MMP8 (NM_002424) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210391L1V

Lenti ORF particles, MMP8 (Myc-DDK tagged) - Human matrix metallopeptidase 8 (neutrophil collagenase) (MMP8), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: MMP8
• Synonyms: CLG1; HNC; MMP-8; PMNL-CL
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_002424
• ORF Size: 1401 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210391).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002424.1, NP_002415.1
• RefSeq Size: 3056
• RefSeq ORF: 1404
• Locus ID: 4317
• Domains: hemopexin, Peptidase_M10, ZnMc
• Protein Families: Druggable Genome, Protease
• MW: 53.4 kDa
• Gene Summary: This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]