Acrosin (ACR) (NM_001097) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC214256L3V
- LentiORF®
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Lenti ORF particles, ACR (Myc-DDK tagged) - Human acrosin (ACR), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | ACR |
Synonyms | acrosin; preproacrosin; proacrosin |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001097 |
ORF Size | 1263 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC214256).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001097.1, NP_001088.1, NP_001088.2 |
RefSeq Size | 1388 bp |
RefSeq ORF | 1266 bp |
Locus ID | 49 |
Cytogenetics | 22q13.33 |
Protein Families | Druggable Genome, Protease |
MW | 45.8 kDa |
Gene Summary | 'Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008]' |
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