Luteinizing Hormone beta (LHB) (NM_000894) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216028L1V

Lenti ORF particles, LHB (Myc-DDK tagged) - Human luteinizing hormone beta polypeptide (LHB), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: LHB
• Synonyms: CGB4; HH23; LSH-B; LSH-beta
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000894
• ORF Size: 423 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216028).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000894.2, NP_000885.1
• RefSeq Size: 523 bp
• RefSeq ORF: 426 bp
• Locus ID: 3972
• Cytogenetics: 19q13.33
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: GnRH signaling pathway, Neuroactive ligand-receptor interaction
• MW: 15.35 kDa
• Gene Summary: 'This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]'