GBA (NM_000157) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216061L1V

Lenti ORF particles, GBA (Myc-DDK tagged) - Human glucosidase, beta, acid (GBA), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GBA
• Synonyms: GBA1; GCB; GLUC
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000157
• ORF Size: 1608 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216061).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000157.2, NP_000148.2
• RefSeq Size: 2324 bp
• RefSeq ORF: 1611 bp
• Locus ID: 2629
• Cytogenetics: 1q22
• Domains: Glyco_hydro_30
• Protein Families: Druggable Genome
• Protein Pathways: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism
• MW: 59.72 kDa
• Gene Summary: 'This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]'