NRG2 (NM_013982) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC216128L1V
- LentiORF®
Lenti ORF particles, NRG2 (Myc-DDK tagged) - Human neuregulin 2 (NRG2), transcript variant 3, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | NRG2 |
Synonyms | DON1; HRG2; NTAK |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_013982 |
ORF Size | 2574 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC216128).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_013982.1, NP_053585.1 |
RefSeq Size | 3044 |
RefSeq ORF | 2577 |
Locus ID | 9542 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | ErbB signaling pathway |
MW | 92.5 kDa |
Gene Summary | This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010] |
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