Gemin 2 (GEMIN2) (NM_001009183) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC216807L3V

Lenti ORF particles, GEMIN2 (Myc-DDK tagged) - Human survival of motor neuron protein interacting protein 1 (SIP1), transcript variant gamma, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: GEMIN2
• Synonyms: SIP1; SIP1-delta
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001009183
• ORF Size: 750 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216807).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001009183.1, NP_001009183.1
• RefSeq Size: 1309 bp
• RefSeq ORF: 720 bp
• Locus ID: 8487
• Cytogenetics: 14q21.1
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 28 kDa
• Gene Summary: This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]