NALP6 (NLRP6) (NM_138329) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217978L3V

Lenti ORF particles, NLRP6 (Myc-DDK-tagged)-Human NLR family, pyrin domain containing 6 (NLRP6), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: NLRP6
• Synonyms: AVR; CLR11.4; NALP6; NAVR; NAVR/AVR; PAN3; PYPAF5
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_138329
• ORF Size: 2676 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217978).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_138329.2, NP_612202.1, NP_612202.2
• RefSeq Size: 2679
• RefSeq ORF: 2679
• Locus ID: 171389
• MW: 98.6 kDa
• Gene Summary: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]