Estrogen Receptor beta (ESR2) (NM_001437) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC218519L1V

Lenti ORF particles, ESR2 (Myc-DDK tagged) - Human estrogen receptor 2 (ER beta) (ESR2), transcript variant a, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ESR2
• Synonyms: ER-BETA; Erb; ESR-BETA; ESRB; ESTRB; NR3A2; ODG8
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001437
• ORF Size: 1590 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC218519).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001437.1, NP_001428.1
• RefSeq Size: 2011 bp
• RefSeq ORF: 1593 bp
• Locus ID: 2100
• Cytogenetics: 14q23.2-q23.3
• Domains: HOLI, zf-C4
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• MW: 59 kDa
• Gene Summary: 'This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]'