BCKDHB (NM_000056) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC218846L3V
- LentiORF®
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Lenti ORF particles, BCKDHB (Myc-DDK tagged) - Human branched chain keto acid dehydrogenase E1, beta polypeptide (BCKDHB), nuclear gene encoding mitochondrial protein, transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | BCKDHB |
Synonyms | BCKDE1B; BCKDH E1-beta; E1B |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_000056 |
ORF Size | 1176 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218846).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000056.2, NP_000047.1 |
RefSeq Size | 1552 bp |
RefSeq ORF | 1179 bp |
Locus ID | 594 |
Cytogenetics | 6q14.1 |
Domains | transket_pyr, transketolase_C |
Protein Pathways | Metabolic pathways, Valine, leucine and isoleucine degradation |
MW | 43.12 kDa |
Gene Summary | 'This gene encodes the E1 beta subunit of branched-chain keto acid dehydrogenase, which is a multienzyme complex associated with the inner membrane of mitochondria. This enzyme complex functions in the catabolism of branched-chain amino acids. Mutations in this gene have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation and feeding problems. Alternative splicing at this locus results in multiple transcript variants. [provided by RefSeq, Jan 2016]' |
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