GCSF Receptor (CSF3R) (NM_156038) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC219104L3V
- LentiORF®
Lenti ORF particles, CSF3R (Myc-DDK tagged) - Human colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | CSF3R |
Synonyms | CD114; CD114 antigen; colony stimulating factor 3 receptor; colony stimulating factor 3 receptor (granulocyte); GCSFR; granulocyte colony stimulating factor receptor; OTTHUMP00000009703; OTTHUMP00000009704; OTTHUMP00000009705 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_156038 |
ORF Size | 2307 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC219104).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_156038.2, NP_724780.2 |
RefSeq Size | 2909 bp |
RefSeq ORF | 2309 bp |
Locus ID | 1441 |
Cytogenetics | 1p34.3 |
Domains | FN3 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Pathways in cancer |
MW | 82.3 kDa |
Gene Summary | 'The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010]' |
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