GABA B Receptor 2 (GABBR2) (NM_005458) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC219404L4V
- LentiORF®
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Lenti ORF particles, GABBR2 (mGFP-tagged) - Human gamma-aminobutyric acid (GABA) B receptor, 2 (GABBR2), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | GABBR2 |
Synonyms | EIEE59; GABABR2; GPR51; GPRC3B; HG20; HRIHFB2099; NDPLHS |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_005458 |
ORF Size | 2823 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC219404).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_005458.5, NP_005449.5 |
RefSeq Size | 5786 |
RefSeq ORF | 2826 |
Locus ID | 9568 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
MW | 105.8 kDa |
Gene Summary | The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence. [provided by RefSeq, Jan 2010] |
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