HOXB8 (NM_024016) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221896L1V

Lenti ORF particles, HOXB8 (Myc-DDK tagged) - Human homeobox B8 (HOXB8), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: HOXB8
• Synonyms: Hox-2.4; HOX2; HOX2D
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_024016
• ORF Size: 254 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221896).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_024016.2, NP_076921.1
• RefSeq Size: 1823 bp
• RefSeq ORF: 732 bp
• Locus ID: 3218
• Cytogenetics: 17q21.32
• Protein Families: ES Cell Differentiation/IPS
• MW: 27.4 kDa
• Gene Summary: 'This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq, Jul 2008]'