PON2 (NM_000305) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC222624L2V

Lenti ORF particles, PON2 (mGFP-tagged) - Human paraoxonase 2 (PON2), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: PON2
• Vector: pLenti-C-mGFP
• ACCN: NM_000305
• ORF Size: 1062 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC222624).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000305.2, NP_000296.2
• RefSeq Size: 1669 bp
• RefSeq ORF: 1065 bp
• Locus ID: 5445
• Cytogenetics: 7q21.3
• Domains: Arylesterase
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways
• MW: 39.2 kDa
• Gene Summary: 'This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]'