ATP7B (NM_000053) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC223635L1V

Lenti ORF particles, ATP7B (Myc-DDK tagged) - Human ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: ATP7B
• Synonyms: PWD; WC1; WD; WND
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_000053
• ORF Size: 4395 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223635).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000053.2, NP_000044.2
• RefSeq Size: 6644
• RefSeq ORF: 4398
• Locus ID: 540
• Domains: E1-E2_ATPase, Hydrolase, HMA
• Protein Families: Druggable Genome, Transmembrane
• MW: 157.1 kDa
• Gene Summary: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008]