Retinoic Acid Receptor beta (RARB) (NM_000965) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC224529L2V
- LentiORF®
Lenti ORF particles, RARB (mGFP-tagged) - Human retinoic acid receptor, beta (RARB), transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | RARB |
Synonyms | HAP; MCOPS12; NR1B2; RARbeta1; RRB2 |
Vector | pLenti-C-mGFP |
ACCN | NM_000965 |
ORF Size | 1344 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC224529).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000965.2, NP_000956.2 |
RefSeq Size | 3222 bp |
RefSeq ORF | 1347 bp |
Locus ID | 5915 |
Cytogenetics | 3p24.2 |
Domains | HOLI, zf-C4 |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways | Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer |
MW | 50.3 kDa |
Gene Summary | 'This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014]' |
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