SARDH (NM_001134707) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC226262L4V

Lenti ORF particles, SARDH (mGFP-tagged)-Human sarcosine dehydrogenase (SARDH), nuclear gene encoding mitochondrial protein, transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: SARDH
• Synonyms: BPR-2; DMGDHL1; SAR; SARD; SDH
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_001134707
• ORF Size: 2754 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC226262).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001134707.1, NP_001128179.1
• RefSeq ORF: 2757 bp
• Locus ID: 1757
• Cytogenetics: 9q34.2
• Protein Pathways: Glycine, serine and threonine metabolism, Metabolic pathways
• MW: 101.04 kDa
• Gene Summary: 'This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2008]'