Phospholipase A2 IIA (PLA2G2A) (NM_001161727) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC228737L3V
- LentiORF®
Lenti ORF particles, PLA2G2A (Myc-DDK-tagged)-Human phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | PLA2G2A |
Synonyms | MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001161727 |
ORF Size | 432 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC228737).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001161727.1, NP_001155199.1 |
RefSeq ORF | 435 bp |
Locus ID | 5320 |
Cytogenetics | 1p36.13 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway |
MW | 16.08 kDa |
Gene Summary | 'The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]' |
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