CYP51A1 (NM_001146152) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC228881L4V
- LentiORF®
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Lenti ORF particles, CYP51A1 (mGFP-tagged)-Human cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | CYP51A1 |
Synonyms | CP51; CYP51; CYPL1; LDM; P450-14DM; P450L1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001146152 |
ORF Size | 1212 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC228881).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001146152.1, NP_001139624.1 |
RefSeq Size | 2934 bp |
RefSeq ORF | 1215 bp |
Locus ID | 1595 |
Cytogenetics | 7q21.2 |
Protein Families | Druggable Genome, P450, Transmembrane |
Protein Pathways | Metabolic pathways, Steroid biosynthesis |
MW | 46.3 kDa |
Gene Summary | 'This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]' |
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