BCAT1 (NM_001178094) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC229972L1V
- LentiORF®
Lenti ORF particles, BCAT1 (Myc-DDK-tagged)-Human branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 5, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | BCAT1 |
Synonyms | BCATC; BCT1; ECA39; MECA39; PNAS121; PP18 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_001178094 |
ORF Size | 1155 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC229972).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001178094.1, NP_001171565.1 |
RefSeq ORF | 1158 bp |
Locus ID | 586 |
Cytogenetics | 12p12.1 |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Pantothenate and CoA biosynthesis, Valine, leucine and isoleucine biosynthesis, Valine, leucine and isoleucine degradation |
MW | 43.3 kDa |
Gene Summary | 'This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]' |
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