PKN beta (PKN3) (NM_013355) Human Mutant ORF Clone

CAT#: RC403205

PKN3 Mutant (W346X), Myc-DDK-tagged ORF clone of Homo sapiens protein kinase N3 (PKN3) as transfection-ready DNA

Specifications

Product Data

• Mutation Description: W346X
• Affected Codon#: 346
• Affected NT#: 1038
• Tag: Myc-DDK
• Effect: Poenil proein defiieny
• Symbol: PKN3
• Synonyms: UTDP4-1
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Vector: pCMV6-Entry
• ACCN: NM_013355
• ORF Size: 1035 bp
• Sequence Data:
  ORF Nucleotide Sequence

  >RC403205 representing NM_013355
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGGAGGGGGCGCCGCGGCAGCCTGGGCCGAGCCAGTGGCCCCCAGAGGATGAGAAGGAGGTGATCC
  GCCGGGCCATCCAGAAAGAGCTGAAGATCAAGGAGGGGGTGGAGAACCTGCGGCGCGTGGCCACAGACCG
  CCGCCACTTGGGCCATGTGCAGCAGCTGCTGCGGTCCTCCAACCGCCGCCTGGAGCAGCTGCATGGCGAG
  CTGCGGGAGCTGCACGCCCGAATCCTGCTGCCCGGCCCTGGGCCTGGCCCAGCTGAGCCTGTGGCCTCAG
  GACCCCGGCCGTGGGCAGAGCAGCTCAGGGCTCGGCACCTAGAGGCTCTCCGGAGGCAGCTGCATGTGGA
  GCTGAAGGTGAAGCAGGGGGCTGAGAACATGACCCACACGTGCGCCAGTGGCACCCCCAAGGAGAGGAAG
  CTCCTGGCAGCTGCCCAGCAGATGCTGCGGGACAGCCAGCTGAAGGTGGCCCTGCTGCGGATGAAGATCA
  GCAGCCTGGAGGCCAGTGGGTCCCCGGAGCCAGGGCCTGAGCTGCTGGCGGAGGAGCTACAGCATCGACT
  GCACGTTGAGGCAGCTGTGGCTGAGGGCGCCAAGAACGTGGTGAAACTGCTTAGTAGCCGGAGAACACAG
  GACCGCAAGGCACTGGCTGAGGCCCAGGCCCAGCTACAGGAGTCCTCTCAGAAACTGGACCTCCTGCGCC
  TGGCCTTGGAGCAGCTGCTGGAGCAACTGCCTCCTGCCCACCCTTTGCGCAGCAGAGTGACCCGAGAGTT
  GCGGGCTGCGGTGCCTGGATACCCCCAGCCTTCAGGGACACCTGTGAAGCCCACCGCCCTAACAGGGACA
  CTGCAGGTCCGCCTCCTGGGCTGTGAACAGTTGCTGACAGCCGTGCCTGGGCGCTCCCCAGCGGCCGCAC
  TGGCCAGCAGCCCCTCCGAGGGCTGGCTTCGGACCAAGGCCAAGCACCAGCGTGGCCGAGGCGAGCTTGC
  CAGCGAGGTGCTGGCTGTGCTAAAGGTGGACAACCGTGTTGTGGGGCAGACGGGC
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGA TAAGGTTTAA
  Protein Sequence

  >RC403205 representing NM_013355
  Red=Cloning site Green=Tags(s)
  
  MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSSNRRLEQLHGE
  LRELHARILLPGPGPGPAEPVASGPRPWAEQLRARHLEALRRQLHVELKVKQGAENMTHTCASGTPKERK
  LLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLAEELQHRLHVEAAVAEGAKNVVKLLSSRRTQ
  DRKALAEAQAQLQESSQKLDLLRLALEQLLEQLPPAHPLRSRVTRELRAAVPGYPQPSGTPVKPTALTGT
  LQVRLLGCEQLLTAVPGRSPAAALASSPSEGWLRTKAKHQRGRGELASEVLAVLKVDNRVVGQTG
  
  SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NP_037487
• RefSeq Size: 1035
• RefSeq ORF: 2670
• Locus ID: 29941
• Protein Families: Druggable Genome, Protein Kinase
• MW: 38 kDa
• Gene Summary: Contributes to invasiveness in malignant prostate cancer. [UniProtKB/Swiss-Prot Function]