Human ACADS activation kit by CRISPRa

CAT#: GA100027

ACADS CRISPRa kit - CRISPR gene activation of human acyl-CoA dehydrogenase short chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACADS
• Locus ID: 35
• Kit Components:

  GA100027G1, ACADS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100027G2, ACADS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100027G3, ACADS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000017, NM_001302554, NM_001302554.2
• Synonyms: ACAD3; SCAD
• Summary: This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms. [provided by RefSeq, Oct 2014]