Human ACADVL activation kit by CRISPRa

CAT#: GA100029

ACADVL CRISPRa kit - CRISPR gene activation of human acyl-CoA dehydrogenase very long chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACADVL
• Locus ID: 37
• Kit Components:

  GA100029G1, ACADVL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100029G2, ACADVL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100029G3, ACADVL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000018, NM_001033859, NM_001270447, NM_001270448
• Synonyms: ACAD6; LCACD; VLCAD
• Summary: The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]