Human ACAT1 activation kit by CRISPRa

CAT#: GA100030

ACAT1 CRISPRa kit - CRISPR gene activation of human acetyl-CoA acetyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACAT1
• Locus ID: 38
• Kit Components:

  GA100030G1, ACAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100030G2, ACAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100030G3, ACAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000019
• Synonyms: ACAT; MAT; T2; THIL
• Summary: This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009]