Human ACAT2 activation kit by CRISPRa

CAT#: GA100031

ACAT2 CRISPRa kit - CRISPR gene activation of human acetyl-CoA acetyltransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACAT2
• Locus ID: 39
• Kit Components:

  GA100031G1, ACAT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100031G2, ACAT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100031G3, ACAT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303253, NM_005891
• Summary: 'The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]'