Human ACCN2 (ASIC1) activation kit by CRISPRa

CAT#: GA100033

ASIC1 CRISPRa kit - CRISPR gene activation of human acid sensing ion channel subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ASIC1
• Locus ID: 41
• Kit Components:

  GA100033G1, ACCN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100033G2, ACCN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100033G3, ACCN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001095, NM_001256830, NM_020039, NR_046389
• Synonyms: ACCN2; ASIC; BNaC2
• Summary: 'This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]'