Human Acid Phosphatase (ACP1) activation kit by CRISPRa

CAT#: GA100040

ACP1 CRISPRa kit - CRISPR gene activation of human acid phosphatase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACP1
• Locus ID: 52
• Kit Components:

  GA100040G1, Acid Phosphatase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100040G2, Acid Phosphatase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100040G3, Acid Phosphatase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001040649, NM_004300, NM_007099, NM_177554, NR_024080
• Synonyms: HAAP
• Summary: 'The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]'