Human ACTN3 activation kit by CRISPRa

CAT#: GA100055

ACTN3 CRISPRa kit - CRISPR gene activation of human actinin alpha 3 (gene/pseudogene)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACTN3
• Locus ID: 89
• Kit Components:

  GA100055G1, ACTN3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100055G2, ACTN3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100055G3, ACTN3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001104, NM_001258371, NR_047663
• Synonyms: MGC117002; MGC117005
• Summary: 'This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status. [provided by RefSeq, Feb 2014]'