Human ACYP2 activation kit by CRISPRa

CAT#: GA100063

ACYP2 CRISPRa kit - CRISPR gene activation of human acylphosphatase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACYP2
• Locus ID: 98
• Kit Components:

  GA100063G1, ACYP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100063G2, ACYP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100063G3, ACYP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001108, NM_001320586, NM_001320587, NM_001320588, NM_001320589, NM_001320590, NM_138448
• Synonyms: ACYM; ACYP
• Summary: Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]