Human ADCY2 activation kit by CRISPRa

CAT#: GA100071

ADCY2 CRISPRa kit - CRISPR gene activation of human adenylate cyclase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADCY2
• Locus ID: 108
• Kit Components:

  GA100071G1, ADCY2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100071G2, ADCY2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100071G3, ADCY2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_020546
• Synonyms: AC2; HBAC2
• Summary: 'This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. [provided by RefSeq, Jul 2008]'