Human ADCY7 activation kit by CRISPRa

CAT#: GA100075

ADCY7 CRISPRa kit - CRISPR gene activation of human adenylate cyclase 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADCY7
• Locus ID: 113
• Kit Components:

  GA100075G1, ADCY7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100075G2, ADCY7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100075G3, ADCY7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001114, NM_001286057
• Synonyms: AC7
• Summary: 'This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013]'