Human ADCY8 activation kit by CRISPRa

CAT#: GA100076

ADCY8 CRISPRa kit - CRISPR gene activation of human adenylate cyclase 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADCY8
• Locus ID: 114
• Kit Components:

  GA100076G1, ADCY8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100076G2, ADCY8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100076G3, ADCY8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001115
• Synonyms: AC8; ADCY3; HBAC1
• Summary: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008]