Human PACAP (ADCYAP1) activation kit by CRISPRa

CAT#: GA100078

ADCYAP1 CRISPRa kit - CRISPR gene activation of human adenylate cyclase activating polypeptide 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADCYAP1
• Locus ID: 116
• Kit Components:

  GA100078G1, PACAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100078G2, PACAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100078G3, PACAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001099733, NM_001117
• Synonyms: PACAP
• Summary: 'This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]'