Human alpha Adducin (ADD1) activation kit by CRISPRa

CAT#: GA100080

ADD1 CRISPRa kit - CRISPR gene activation of human adducin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADD1
• Locus ID: 118
• Kit Components:

  GA100080G1, alpha Adducin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100080G2, alpha Adducin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100080G3, alpha Adducin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001119, NM_001286645, NM_014189, NM_014190, NM_176801, NM_001354754, NM_001354755, NM_001354756, NM_001354757, NM_001354758, NM_001354759, NM_001354761, NM_001354762
• Synonyms: ADDA
• Summary: 'Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]'