Human ADH1C activation kit by CRISPRa

CAT#: GA100086

ADH1C CRISPRa kit - CRISPR gene activation of human alcohol dehydrogenase 1C (class I), gamma polypeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADH1C
• Locus ID: 126
• Kit Components:

  GA100086G1, ADH1C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100086G2, ADH1C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100086G3, ADH1C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000669, NR_133005
• Synonyms: ADH3
• Summary: This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]